The focus of this course is human metabolism. Students will learn the major metabolic pathways that are used to acquire and utilize the free energy that is needed to carry out various physiological functions. Metabolism will be presented at the systems-level to highlight the interrelationships of pathways. Emphasis will be placed on metabolic regulation and the influence that this regulation has on human health. The role metabolism plays in diabetes and cancer will be studied in detail. Modern technologies used to study metabolism will also be covered. Students will learn how to apply these technologies to understand metabolic perturbations associated with disease. Prerequisite: Chem 481 or Biol 4810.